It also highlights the interprofessional team's role in managing lorazepam therapy. This activity covers lorazepam, including mechanism of action, pharmacology, adverse event profiles, eligible patient populations, and monitoring. Off-label (non-FDA-approved) uses for lorazepam include rapid tranquilization of the agitated patient, alcohol withdrawal delirium, alcohol withdrawal syndrome, insomnia, panic disorder, delirium, chemotherapy-associated anticipatory nausea, and vomiting (adjunct or breakthrough), as well as psychogenic catatonia. Lorazepam is FDA-approved for short-term (4 months) relief of anxiety symptoms related to anxiety disorders, anxiety-associated insomnia, anesthesia premedication in adults to relieve anxiety or to produce sedation/amnesia, and treatment of status epilepticus.
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